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Laboratory 17

Publications · In plain words

Microalgae and cyanobacteria: biological effects on animal somatic cells and antimicrobial potential

Lykov A. P., Gevorgiz R. G., Zheleznova S. N., Uvarov I. P. · Algae: Problems of Taxonomy and Ecology, Use in Monitoring and Biotechnology. Proceedings of the 7th All-Russian Scientific Conference with International Participation, Vladivostok, 16–20 September 2024, p. 74

In Russian

What this work is about, in plain words

An overview abstract of the group's research: how extracts of microalgae and cyanobacteria of different groups act on mice, their cells and bacteria.

In this abstract, the authors briefly summarized their work on the biological action of microalgae and cyanobacteria. The aim was to show how cultures of different groups and habitats affect animal cells and microbes.

The experiments included green algae (Chlorella vulgaris, Coelastrella sp., Tetraselmis viridis), cyanobacteria (Arthrospira platensis, Leptolyngbya cf. ectocarpi, Planktothrix agardhii, Roholtiella mixta), diatoms (Cylindrotheca closterium, Nanofrustulum shiloi) and the red alga Porphyridium purpureum. Substances were extracted with vegetable oil, alcohol or DMSO solution. Oil extracts were given to mice with feed, fucoxanthin extracts by mouth, and the rest were tested on cells and bacteria in vitro.

According to the authors, oil extracts changed blood levels of proteins, fats and sex hormones in mice, and substances from the algae changed the production of inflammatory and anti-inflammatory cytokines in the blood, liver and kidneys. They also affected the viability and function of lymphocytes and monocytes and suppressed the growth of some bacteria and mycobacteria. Fucoxanthin extracts changed a number of blood biochemical parameters and interleukin levels.

Limitations. The abstract is a short summary of already published experiments without figures or methods; details are in the articles in this library. Experiments on mice and cells, not on humans. The results were obtained by the authors and do not describe Laboratory 17 materials.

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